PM2PY3-Clinical Therapeutics 2

Module Provider: Pharmacy
Number of credits: 40 [20 ECTS credits]
Level:5
Terms in which taught: Spring term module
Pre-requisites: PM1A Fundamentals of Physiology and PM1B Medicines Discovery, Design, Development and Delivery and PM1C Introduction to Professionalism and Practice
Non-modular pre-requisites:
Co-requisites: PM2PY1 Professional Practice 2 and PM2PY2 Clinical Therapeutics 1
Modules excluded:
Current from: 2023/4

Module Convenor: Dr Silvia Amadesi
Email: s.amadesi@reading.ac.uk

Type of module:

Summary module description:

This module introduces students to the therapeutic themes of cardiovascular and renal diseases and integrates the science into clinical practice. Students build on knowledge gained in Part 1 modules that introduce cell biology and physiological systems and drug design and formulation. Students learn about the anatomy and pathology of diseases that affect the cardiovascular and renal systems and how they are managed therapeutically, including pharmaceutical care and patient management issues, application of pharmaceutical principles, drug design and pharmaceutical analysis, aseptics and manufacturing.

Aims:

This module aims to provide students with an understanding of human cardiovascular and renal diseases and related therapeutics with strong integration of physiology themes taught during the first year. The module also provides the basis for the therapeutics modules taught in elsewhere in the programme. To achieve that, the core science concepts detailed in the summary above will be taught using an appropriate range of teaching activities to allow integration of the disciplines that link to the therapeutic topics of the module.

Assessable learning outcomes:

At the end of the module the student will be expected to:

1. Describe the anatomy, physiology, aetiology, diagnosis and therapeutics of cardiovascular and renal disease.


2. Discuss the pharmaceutical management of the conditions incorporating all relevant aspects of teaching including pharmacology.


3. Apply the pharmaceutical principles of drug design.


4. Demonstrate a knowledge of pharmaceutical analysis including processes of quality assurance and quality control.


5. Explain the role of pharmacy technical services and the processes and techniques used in the aseptic preparation of medicinal products.


6. Undertake a case-based presentation whilst considering the psychological, physiological and physical impact of prescribing decisions on patients.

Additional outcomes:

Students should be able to:

• Discuss the different administration routes and formulations for the cardiovascular and renal systems.


• Manage project work and maintain appropriate records demonstrating professional practice.


• Take responsibility for Health and Safety and work as teams.


• Interpret and use clinical guidance and recognise and use reliable sources for information retrieval.


• Recognise different types of journal articles, how they differ and how they should be used.


• Consider sustainability in their medicine and device choices whilst recognising that


• medicines optimisation is also an important sustainability tool that complements patient care.

Outline content:

This module introduces the therapeutics of cardiovascular and renal diseases. An appropriate range of lectures, tutorials, practical classes, group working and guided individual study will be used to achieve the learning outcomes and also integrate with those of previous modules, helping to contextualise relevance to the practice of pharmacy. The students will also undertake interprofessional education with other health professional students.

Content that will be covered includes: therapeutics of common drugs used to treat diseases of the cardiovascular and renal systems, the anatomy, aetiology and pathology of the major diseases associated with these systems; case studies in drug design and drug development to market; quality assurance and quality control in the process of medicine manufacturing, including an overview of analytical methods and testing. The module also contains an integrated practical component in which students will write a chemical analysis and physical testing report.

Global context:

This module will develop core knowledge and show how this knowledge is relevant to the role of a pharmacist. The student will need to develop independent learning skills within this module to progress into Part 3 but should then be suitably equipped to tackle the rigour of an MPharm degree. The topics covered here will link into all modules of Parts 2 and 3.

Brief description of teaching and learning methods:

The learning outcomes will be met through a mixture of lectures, tutorials, group work, directed private study, self-directed learning, as well as practical-based laboratory classes. Some of the lectures or tutorials will utilise a case-based learning-like approach: activities will adopt characteristics of workshops where students will engage in formative activities e.g., group work, in-class discussion. Appropriate supplementary information and reading lists will be provided and facilities f or computer-aided literature searching for additional relevant materials will enable students to improve their own learning skills. 

Contact hours:

	Autumn	Spring	Summer
Lectures		50
Tutorials		3
Practicals classes and workshops		18
Supervised time in studio/workshop		29
Guided independent study:
Wider reading (independent)		150
Wider reading (directed)		40
Advance preparation for classes		10
Preparation for tutorials		5
Preparation of practical report		15
Completion of formative assessment tasks		5
Revision and preparation		47	3
Group study tasks		20
Reflection		5
Total hours by term	0	397	3
Total hours for module	400

Summative Assessment Methods:

Method	Percentage
Written exam	70
Report	20
Set exercise	10

Summative assessment- Examinations:

In the summer exam period:

Written examination - (70% of module) - 2 hrs

Summative assessment- Coursework and in-class tests:

1. Integrated practical report (20% of module)


2. Set exercise (care plan) (10% of module) 

Formative assessment methods:

Formative assessment is largely based on coursework and self-directed assessment and will reinforce each of the learning outcomes of the module. These will be staff, peer, or self- assessed and will include laboratory worksheets, written and online assignments. These assessments will provide students with feedback on their achievement of the learning outcomes and prepare them for the summative assessments.

Penalties for late submission:

The Support Centres will apply the following penalties for work submitted late:

• where the piece of work is submitted after the original deadline (or any formally agreed extension to the deadline): 10% of the total marks available for that piece of work will be deducted from the mark for each working day (or part thereof) following the deadline up to a total of five working days;
• where the piece of work is submitted more than five working days after the original deadline (or any formally agreed extension to the deadline): a mark of zero will be recorded.

The University policy statement on penalties for late submission can be found at: https://www.reading.ac.uk/cqsd/-/media/project/functions/cqsd/documents/cqsd-old-site-documents/penaltiesforlatesubmission.pdf
You are strongly advised to ensure that coursework is submitted by the relevant deadline. You should note that it is advisable to submit work in an unfinished state rather than to fail to submit any work.

Assessment requirements for a pass:

All summative assessments must be passed at 40%.

Reassessment arrangements:

Re-examination (written paper) in August.  Failed coursework assessment may be reassessed by an alternative piece of work, before or during the August examination period.

Additional Costs (specified where applicable):

1) Required text books: 

2) Specialist equipment or materials: 

3) Specialist clothing, footwear or headgear: 

4) Printing and binding: 

5) Computers and devices with a particular specification: 

6) Travel, accommodation and subsistence: 

Last updated: 4 September 2023